Educational Forum with Clinical Studies Current Science and Research

Lara Grinevitch BSc, ND; 2007

These were the headlines in the media last month, and they were very misleading. There was never any suggestion that natural progesterone causes cancer. The concern about cancer is a concern about oestradiol (a strong oestrogen that is used in some, but not all, bio-identical hormone formulas). If a troche does contain oestradiol, then there is a risk for the breasts and the uterus. Natural progesterone offsets the risk for the breasts, but the conventional medical community in Australia argues that it does not protect the uterus. The Medical Journal of Australia put forward three cases of stage 1 endometrial cancer in women who had used oestradiol-containing troches. (1). (Stage 1 endometrial cancer is relatively mild, and is expected to have a good outcome.) No definitive proof is available that the troches had been the cause of the cancer. The women had been on the troches for 18 months, 3 years and 6 years. Yes, it is true that oestradiol supplements require progesterone to reduce the risk of endometrial cancer. Artificial progesterone, called progestin, was introduced as part of HRT in the 1960’s to do just that. It was a pharmaceutical band-aid for the epidemic of endometrial cancer that had resulted from conventional oestrogen HRT. Natural progesterone would have been the more logical choice at that time (because protecting the endometrium is one of progesterone’s normal jobs in the body). And natural progesterone would have had another benefit, had it become part of conventional HRT: Natural progesterone also protects against BREAST CANCER. (Progestins do the opposite: They INCREASE the risk for breast cancer.) The protective effect on the breasts is the main reason that natural health practitioners prefer natural progesterone to progestin.Although natural progesterone could have been the logical choice for endometrial cancer prevention all along, there were two reasons why it was not initially used: 1) At the time that Progestins were introduced (1960’s), natural progesterone was not available except by injection. 2) As a natural hormone, progesterone was not patentable. Today, technology allows progesterone to be absorbed through the skin or ingested. There is evidence that it is absorbed, and there is evidence that it does protect against endometrial cancer (2,3). In parts of Europe, ‘micronised progesterone’ (natural progesterone) has become standard care in gynaecology. The fact that it remains a fringe prescription in Australia is more to do with entrenched practice than medical science

Xanya Sofra Weiss

Xanya Sofra Weiss

First the basic facts:
1. Only hydrogen can create the free proton, H+. It is a law of the universe. Water contains protons that can be donated to a reaction. Water disassociates into H+ and OH-.
2. The presence of protons, H+ has everything to do with acidic pH measurements and oxidation- reduction potential measurements (ORP). If you measure an acidic pH and a positive ORP in pure water you have free protons.
3. For every electron involved in a reaction, a proton, H+ must be donated to the set of oxidation-reduction reactions to keep the system electrically balanced. That is a law of oxidation – reduction reactions. The Krebs cycle is nothing but coupled oxidation- reduction reactions. Protons drive the Krebs cycle.
4. The mitochondria and the Krebs cycle must have protons or your body can not produce energy and you die. It is called the proton motive force. Dr. Krebs won a noble prize for this discovery.
5. Proton Donors are nothing more complicated then being a source of protons to the mitochondria. Not all hydrogen containing compounds can be proton donors. It all depends on the size, shape and chemical composition of the molecule as to whether the proton can be donated. Indisputable fact about the role of the B-vitamins in the body; they are proton donors while other vitamins are not. People lack energy when they are short on B-vitamins.
6. Cell water is a source of protons to the enzymes of the Krebs cycle and cell water keeps the enzymes the proper distance apart from each other. Cell water is structured water that actively participates in the enzymatic reactions of the Krebs cycle by being a source of protons, in other words, cell water is a proton donor. Hydrate2o is designed to mimic cell water in all its functions, hydration and proton donor capacity.

Xanya Sofra Weiss

Xanya Sofra Weiss

Kim D. Kelly, ND, MPH

• Cholesterol – source of all the hormones.
• Hormones play many roles in health and maintenance of body
a) Metabolism of carbohydrates, fats, minerals, proteins, water
b) Regulate DNA and RNA production
c) Regulate body’s response to stress, kidney function, blood sugar blance, menstruation and sexual
function
• As we age hormone production in body declines.

Hormonal imbalances
• Hormonal imbalances compromise not only physical health but also psychological health.
• Our body compensates for imbalances by overproducing key hormones and by converting sex
hormones to stress hormones.

Several causes of hormonal imbalance:
• Nutritional deficiencies
• Lack of exercise
• Exposure to toxins
• STRESS!
• Physiological endocrine disorders
• Sleep disorders
• Exposure to EMF
• Lack of sunlight
• Hypothyroidism
• Insulin resistance
• OTC and prescription medications

Xanya Sofra Weiss

Xanya Sofra Weiss

A new study shows that blood flow to the legs is relatively normal in people with diastolic heart failure, suggesting other potential causes of their inability to do everyday activities, according to researchers at Wake Forest University Baptist Medical Center. “Reduced tolerance for physical activity is the primary symptom of diastolic heart failure, and it greatly affects quality of life,” said Dalane Kitzman, M.D., professor of cardiology and senior researcher on the study. “This condition will increase as our population ages, so it’s important to pinpoint the reasons for their symptoms and to develop effective treatments.

Xanya Sofra Weiss

Xanya Sofra Weiss

We describe the association of recurrent complicated febrile convulsions, developmental delay, ataxia, and obesity in three unrelated girls. The three girls, aged 3 to 4 years, were all born to healthy, nonconsanguineous parents and have normal siblings. Their birth weight was appropriate for gestational age. They are not dysmorphic and have normal head circumference. Development is delayed; they all walked with an ataxic gait after the age of 2 years and started speaking at 3 years. Their growth charts are remarkably alike: they initially had a normal growth curve and around 24 months of age started to gain weight excessively. They all continue to suffer from complicated febrile seizures, which started before 12 months of age, and are resistant to prophylactic anticonvulsants. Metabolic evaluation is normal. They have normal magnetic resonance images and electroencephalograms. Fragile X and Prader-Willi syndromes were ruled out. We suggest that this is a new mental retardation syndrome that should be considered in children with recurrent febrile convulsions, developmental delay, and obesity. In a recent study, mutations in the beta4 calcium channel were identified in the mutant epileptic mouse that presents with epilepsy, mental retardation, and ataxia. We hypothesize that a calcium channel gene may be involved in this syndrome.

Xanya Sofra Weiss

Xanya Sofra Weiss